In general, the common sites of metastases of breast cancer followed by lung and pleura, bone, skin and soft tissue, liver, brain. For the different parts of the transfer, its treatment methods and therapeutic effects vary.
Lung breast cancer the most common sites of metastases. Generally start with the performance of dry cough, chest tightness, shortness of breath and so on antibiotic treatment ineffective. Commonly used method for the treatment of chemotherapy, generally make more than 60% of patients with lesions in the short term to reduce or to completely subside.
Pleural metastasis usually manifested as pleural effusion, pleural puncture may be out of effusion, while injection of chemotherapy drugs to do the chest cavity. Drugs are often used in carboplatin, etc. can also use anti-cancer medicine Elemene or biological agents such as tumor necrosis factor and so on. Usually have a good short-term effect. These two parts of the transfer, through the rationalization of treatment, the general long-term effects are also quite good. Most cases can be maintained with 2-3 years of survival, a few or even up to 7-8 years.
Bone metastasis is also very common, generally thoracolumbar spine, pelvis and ribs in the transfer of more common. Performance parts for the damaged bone pain. Common and effective method for endocrine therapy, isotope therapy, radiotherapy, chemotherapy and double-phosphate. Endocrine therapy can balance the body to other organs, while the isotope treatment only bone, radiotherapy makes the exposed parts of the normal organ has been damaged by the dose-limiting and the site limitations, and therefore often used only for pain treatment. Pairs of phosphate on the pain and inhibiting bone destruction and reduce the incidence of bone metastasis-related effects of a good, long-term use may also be useful for long-term survival of patients. Although bone metastases are more serious, but if you do not associated with other parts of the transfer, such cases usually develop more slowly, and the sensitivity of the various treatments, after reasonable treatment may get unexpected long-term survival. Skin, soft tissue transfer, generally chemotherapy, endocrine sensitive, near-term results better. It should be noted that some patients show only a beginning for a number of isolated metastases, such as the clavicle or local area of a single metastasis. It was only added to the surgical resection and radiotherapy and leave, it ignores a very important systemic treatment, the results soon appeared the second, third … a metastasis.
Metastatic chemotherapy and endocrine therapy generally are not too sensitive, the use of interventional therapy can often obtain better short-term effect, but the extension of their survival is not too obvious. Poor prognosis of brain metastases in general, often with radiotherapy.
Of course, the advanced breast cancer can achieve the desired therapeutic effect, and rational treatment strategies are very important. Someone wants to in order to achieve a good effect, often to chemotherapy, endocrine therapy, radiotherapy, traditional Chinese medicine treatment together simultaneously. This is in fact an item of which treatment is assured to the heart at the end, not only backfire, resulting in waste, but also to cause difficulties later for further treatment. Clinical experience has shown that the treatment strategy, rather than adopting a “100 meters sprint,” might as well adopt a “relay.” Because of different treatment regimens different mechanism of action, while effective use and can not be added to the effect, but one after one use but makes the patients after the failure of a treatment there are always new methods to win the longest survival period .
