Gene identification can help to develop cancer treatment. Thumb A large glass (chips) on the luminescence of the dark spots contribute to the diagnosis and treatment of breast cancer. Through the tumor which genes are activated on the dark spots can help doctors to develop the best, minimal side effects treatment programs.
In the United States and the United Kingdom about 1 / 10 of women with breast cancer, in which half of the patients will have died. Simply by observation of tumor appearance, tumor experts is hard to determine which tumors would spread. Therefore, most women accept the toxic side-effects of hormones and chemical drugs, combination therapy to prevent the cancer cells invade other parts of the body.
However, statistics show that only 20% of cancer patients in need of such treatment of the most painful, most women, the degree of malignancy of breast cancer is not so high, do not need such extreme treatments. Cancer geneticist at Cambridge University, Dr. Samuel said, “These cancer patients only need radiation therapy or surgery can cure.”
Recently, Washington, Steven, Ph.D., and colleagues developed a gene expression by cancer, to identify the highly malignant breast cancer chip method, if the clinical trial is successful, the technology can greatly reduce the number of patients receiving unnecessary treatment.
Malignant tumors genetic profile
Gene chip was covered with a layer of DNA chains has been embellished, when these DNA and its complementary mRNA strand binding, the chip will be light, this mRNA is a gene active in cancer cells generated. This chip can be shown active genes.
By using gene chips handle 78 kinds of breast cancer samples, Stephen’s team established a highly malignant breast cancer genes, it also found that breast cancer is different from other types of breast cancer clues.
Dr. Carlos Caldas University of Cambridge predicted the future, we will be the same as the treatment of infectious diseases to treat cancer. For example, if some cancer cells and expression of androgen receptor gene, the male hormones they stimulate the growth of these tumors and can be inhibited hormone therapy. The Study Group also depicts a common breast cancer carrying the BRCA1 gene related to tumor characteristics. This knowledge enables us to select the most appropriate cancer treatment programs, like selection of antibiotics to kill some bacteria, like.
Universal gene chip
Although very promising, but Stephen’s gene chips are too expensive, can not be used for a wide range of breast cancer screening population. Moreover, the research team only to predict their patients, in which gene chip to enter clinical ago, but also recently was diagnosed with breast cancer patients with a large number of further tests.
Even so, depicts the genetic map of a tumor oncology is bound to become the future direction of development. To judge a person will suffer from what type of cancer on a person’s long-term survival.
“This technology can, should and is being used on other types of tumors.” Dr. Samuel said he has begun to study lymphoma related work, and then will also study other types of tumors
