Breast cancer is one of the most common malignancy of women, according to statistics, the incidence rate of the body a variety of malignant tumors 7-10% in women, second only to uterine cancer.
What types of breast cancer do? By organizational type points, the type of breast cancer are the following:
1. Type of breast cancer non-invasive cancer: the early stages of breast cancer, when the carcinoma confined to the breast ducts or acini, the basement membrane, said no breakthrough in its non-invasive carcinoma.
2. The type of early stage invasive breast cancer:
(1) an early invasive lobular carcinoma: carcinoma of the basement membrane break through the wall and began to interlobular stromal invasion, it is still confined within the lobule.
(2) an early invasive ductal carcinoma: intraductal carcinoma of the cancer cells break through the basement membrane wall and started budding, to interstitial infiltration.
3. The type of breast cancer a special type of invasive carcinoma:
(1) papillary carcinoma: occurs in large duct epithelial cells, cancer, fiber connections in real terms in order to have control or non-papillary fiber bundle structure of the main vein, could a non-invasive and invasive papillary carcinoma. Its infiltration are often present in the base of papillary hyperplasia.
(2) medullary carcinoma accompanied by a large number of lymphocytic infiltration: aspect often necrosis and hemorrhage, microscope, large areas of stromal cells in a large number of lymphocytes and plasma cells infiltration. Peripheral to carcinoma is more obvious, is generally considered to produce the body of tumor resistance.
(3) Small duct carcinoma: occurs in catheter or small duct epithelial cells, is a type of low-grade malignant, prognosis is good.
(4) adenoid cystic carcinoma: Basal cell-like cells from the formation of the size, shape blocks or small pieces of varying dye, the number within the range, size, more consistent circular lacuna. Cavity surface-and cell-chip peripheral blocks of myoepithelial cells can be seen.
(5) sweat adenoid carcinoma: cancer cells rich in cytoplasm, eosinophilic, and sometimes can be seen apocrine protrusions shaped nuclei with mild to moderate form a tubular, acinar or small papillary structures.
(6) mucinous adenocarcinoma: occurs in mammary gland ductal epithelial mucus metaplasia, based on the more common near the menopause or post-menopausal women, especially women over 60 years of age more common. Parenchyma carcinoma, epithelial mucus components accounted for more than half the amount. Mucous vast majority of the cells, the formation of mucus lake; occasionally in cells, showing signet-ring-like cells.
(7) squamous cell carcinoma: from squamous metaplasia of the ductal epithelium. Cancer, all in real terms for a typical squamous cell carcinoma, you can see the intercellular bridges and keratinization. If some other type of cancer, squamous metaplasia occurs is not on that list.
(8) the nipple Paget’s disease: eczema, also known as papillary carcinoma, Paget (1874) first described the disease. After years of research, currently considered the microscopic tumor cells form a bulky, abundant pale staining cytoplasm, Changcheng vacuolar, nuclear large, obviously irregular, occasionally mitotic figures.
4. The type of invasive breast cancer, non-specific cancer
(1) invasive lobular carcinoma: lobular carcinoma lobular obvious to outside infiltration, including small cell carcinoma.
(2) invasive ductal carcinoma: infiltrating ductal carcinoma of clear interstitial, but the invasive part of the substance does not exceed half of cancer. If more than half, places the main form of invasive carcinoma of naming.
(3) Hard cancer: cancer cells are arranged in slender beams or scattered and rarely formed adenoid structures, fibrous stromal component accounted for more than two thirds, and dense.
(4) medullary carcinoma: cancer nest was massive dense sheet or groups, may have adenoid structure, cancer accounted for more than two thirds in real terms, may have a small amount of interstitial lymphocytes and plasma cells.
(5) pure cancer; between hard-cancer and medullary carcinoma, and that means in real terms and fibers, mesenchymal cancer, the proportion of similar composition. Cancer cells mainly formed irregular solid-section beam or a small dye, may also have adenoid structure.
(6) adenocarcinoma: cancer is still the same size, abundant cytoplasm can be secreted, nuclear deep-dyed, karyokinesis more common, cancer cells showed duct-like arrangement, many levels, and polar disorder, lack of basement membrane, in the inter – cytoplasm showed invasive growth of cancer cells also showed cord-chip blocks arranged in duct-like arrangement should take up no more than half.
