Postoperative chemotherapy for all patients with breast cancer are not effective, semi-breast cancer causes over-treatment for all! 80% of all breast cancer patients undergo chemotherapy after surgery, but from the head point of view, and a half is not sensitive to chemotherapy patients, for them, a side effect of chemotherapy is far in the therapeutic effect. The latest view is that the international community to neo-adjuvant chemotherapy, or chemotherapy before surgery on the one hand, can determine whether patients with chemotherapy-sensitive. Effective, as with drugs do “skin test” the same; the other hand, preoperative chemotherapy may the majority of primary breast cancer significantly reduced the volume and improve breast-conserving opportunities.
Breast cancer patients receiving chemotherapy treatment, there will be a series of post-operative response. Itself, the incidence of breast cancer in female patients on so much psychological torture, if not dealt with properly after concurrent problems, will increase the burden even more for patients. So, right after chemotherapy in breast cancer patients should be carefully care.
Due to chemotherapy side effects, and may bring about serious consequences of infertility, many patients tolerated the treatment very difficult, so always want to replace in other ways, but for some breast cancer chemotherapy patients, meaning still significant.
1. Neoadjuvant chemotherapy for breast cancer, the purpose of:
Lower tumor stage, reducing the ratio of radical mastectomy and increase opportunities for breast-conserving surgery
Chemotherapy drugs to determine the clinical and biological markers of
Prognosis
The medical treatment of breast cancer, including chemotherapy (targeted therapy), and endocrine therapy. Can be divided according to status of chemotherapy in patients with neo-adjuvant chemotherapy, adjuvant chemotherapy and rescue therapy. Of these, postoperative adjuvant chemotherapy after 20 years of development, the program from the CMF to anthracycline (doxorubicin, etc.), to the taxane, and targeted drug, clinical research and practice have been proven to improve patient survival and reduce the relapse rate and mortality.
The clinical treatment of cancer chemotherapy is one of the methods commonly used in breast cancer is no exception. Clinicians treating liver cancer with chemotherapy drugs chemotherapy drugs due to rapid growth can be killed or wounded in the malignant cells. However, the toxicity of chemotherapy drugs are usually relatively large class of drugs.
At present, surgery remains the primary means of treatment of breast cancer. But the basic and clinical studies have confirmed the clinical diagnosis of breast cancer, when 50% ~ 60% had micro-metastasis exists, a simple surgery can not cure breast cancer. Therefore, as a systemic chemotherapy treatment increasingly taken seriously. Preoperative chemotherapy can contribute to breast tumors and metastases in local shrink, expand the scope of surgical indications and narrow surgical; also reduces the activity of cancer cells to prevent intraoperative spread of tumor cells, the control is not found in the clinical micro-metastasis, to reduce breast cancer metastasis; and tips used in cancer chemotherapy for the sensitivity. Practice confirmed that preoperative chemotherapy has reduced the advantages of staging. They wanted the smooth progress of chemotherapy, nursing care is essential.
Breast cancer patients receiving radiotherapy and chemical therapy in large numbers, in the process of tumor suppression, bone marrow, gastrointestinal mucosa, central nervous system and heart, liver, kidney function have some of the damage.
The appropriateness of neo-adjuvant chemotherapy group
Generally suitable for clinical IIB, III stage breast cancer. I, IIA patients with the significance of preoperative chemotherapy remains uncertain. IV patients with chemotherapy as the main treatment, rather than secondary treatment.
Bank of occult breast cancer neoadjuvant chemotherapy is feasible.
Breast cancer chemotherapy, including preoperative neoadjuvant chemotherapy and postoperative adjuvant chemotherapy is the comprehensive treatment of breast cancer an important part of belonging to systemic therapy. Chemotherapy usually takes 6-8 cycles (usually 21 days for a cycle), is a comprehensive course of treatment in patients with a long painful period, the need closely with physicians and patients, especially in many patients taking the out-patient chemotherapy, as handled carelessly, may be more serious complications.
