The real cause of breast cancer has not yet accurate research results, but if the patient’s blood or tissue containing BRCA-1 gene mutation, their children can also be found in BRCA-1 gene mutation, then her children would be thrown into a high-risk state. Fudan University Cancer Hospital is about to open on the BRCA-1 mutations in clinic for family history of breast cancer test whether the population genetic mutation.
Breast cancer etiology and estrogen and progesterone hormones, their incidence and diet, obesity and genetic background. One containing the genetic mutation BRCA-1 gene in human, the lifetime chance of breast cancer occurred more than 80%, relatively early age of onset, accompanied by greater opportunities for ovarian cancer.
The study found that if the mother and the first generation of immediate family in post-menopausal breast cancer, breast cancer, then the children the opportunity to place 20% more than the normal population. If the mother took place in pre-menopausal breast cancer, breast cancer occurs more chances then the children, twice as much. If the mother with unilateral breast cancer occurs, children, the chance of breast cancer occurred more than 1 times than the common people only; if the mother pre-menopausal bilateral breast cancer occurs, then opportunities for their children is a normal occurrence of breast cancer 7 ~ 8 times the population, these people are often existence of gene mutation, should cause a high degree of vigilance.