The vast majority of the Department of malignant breast epithelial tissue derived from the mammary gland (breast), a few can be derived from a variety of non-epithelial tissue of breast (various sarcoma), even cancer can be seen mixed sarcoma. The incidence of breast cancer in our country second only to cervical cancer, the incidence of 23/10 million people; accounting for a variety of malignant tumors of the body 7 ~ 10%.
Like breast cancer and other cancers, often through the lymphatic or hematogenous spread to other parts.
(1) lymph node metastasis: axillary lymph nodes and internal mammary lymph node is the first one stop breast cancer metastasis. Patients with breast cancer a high rate of axillary lymph node metastasis and clinical reports in patients with breast cancer treatment when 50% ~ 70% had axillary lymph node metastasis. Axillary lymph node metastasis and the size of primary tumor, tumor size greater the higher the rate of axillary lymph node metastasis, transfer a few more.
Internal mammary lymph node metastasis rate and the tumor location and stage of disease related. It was reported that breast cancer lesions were located outside of their internal mammary lymph node metastasis rate was 12 顎 9%, lesions were located in the center of its transfer rate of 22%, lesions were located in the inside of the transfer rate of 21 顎 9%. With axillary lymph node metastasis of the patients the rate of internal mammary lymph node metastasis is also increased.
Supraclavicular lymph nodes of breast lymphatic drainage is the first two stations, which transfers are mainly via the axillary lymph nodes or internal mammary lymph nodes, mostly ipsilateral, may be transferred to the contralateral supraclavicular lymph nodes.
Tumor cells can also be transferred to the opposite way through the retrograde axillary or inguinal lymph nodes.
(2) hematogenous metastasis: invasive breast cancer cells can be directly caused by blood vessels distant metastasis. The incidence of distant metastasis and primary tumor size, lymph node size and pathological grading. The most common distant metastasis of the lung, followed by bone, pleura, liver, brain, adrenal gland, etc.. Although prone to lymph node metastasis of breast cancer and blood-line transfer, but as long as to take effective preventive measures can be effective in control of their shift.
