The International Cancer Society study found that the incidence of breast cancer with another gene-related factors, such genes are BP1, which exists in 80% of breast cancer tissues and cells. In the study, 57% of white patients with breast cancer the gene produced positive results, while the positive rate of black patients is as high as 89%.
According to the research said that in breast cancer, BP1 expression via an unusual manner, currently available test results of 46 samples were relatively stable. In 9 cases of normal breast samples tested, only one case presented “expression”, that in this case, BP1 gene has been “wake up.” The researchers said, that other breast cancer genes have been found is the same, BP1 gene in the fetal state, have already been activated, but later was closed.
Such as the BP1 gene transcription function, can activate other genes that can produce a kind of a command and functional proteins. This protein can be turned on or off other genes. In some early studies, it was found in leukemia BP1 is usually active, and some laboratories are developing some allow BP1 back to sleep medication.
The discovery of genes contribute to breast cancer, early diagnosis and treatment. The researchers found that this gene both in the original form or in advanced breast cancer has entered the very lively. Preliminary analysis also found that all estrogen receptor-negative breast cancer genetic test results of its BP1 were positive. The researchers said there are two main types of breast cancer, a way to combat estrogen therapy, there is a kind of estrogen therapy is not confrontational. Estrogen receptor-negative tumors more easily treated, for some commonly used anti-breast cancer drugs such as tamoxifen responsive. The estrogen receptor-negative breast cancer cases in the whole breast cancer accounted for 40%. Thus, BP1 discovery for the treatment of these breast cancer provides a new approach.
Vitamin D breast cancer cells can be killer
Way using radiotherapy treatment of breast cancer at the same time, plus vitamin D can be more effective in killing breast cancer cells. In the treatment of breast cancer, doctors often use radiation before surgical treatment methods in order to reduce Aikuai and prevent cancer recurrence after surgery.
Vitamin D on the growth of breast and prostate cancer cells with interference effect. Because taking large doses of natural vitamin D will have a greater toxicity, so researchers used vitamin D analogues will soon be transformed into the natural vitamin D less toxic substances. As the use of vitamin D can be increased by 30% of the radiation effect, thus helping to reduce the number of radiotherapy.
The new gene could trigger breast cancer research can help the treatment of breast cancer, breast cancer patients with the disease should eat more vitamin D class of substances is due to trace levels in food, so patients do not have to worry about to eat more will be poisoned.
